Doxylamine is probably one of the hypnotic compounds which are used extensively by patients as an OTC therapy for insomnia [43] . The antihistamine diphenhydramine has been used for over sixty years in multisymptom medicines to manage cough [44] . The antihistamines doxylamine and chlorpheniramine have been shown to be efficient in relieving sneezing in all probability by peripheral and central anticholinergic actions [45] [46] . The efficacy of triple treatment (ibuprofen, pseudoephedrine and chlorpheniramine) in kids with allergic rhinitis, ...
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